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Fluka
Aniline
51788 -
analytical standard
DOWNLOAD MSDS (PDF)CAS Number: 62-53-3
Linear Formula: C6H5NH2
Molecular Weight: 93.13
Beilstein Registry Number: 605631
EC Number: 200-539-3
MDL number: MFCD00007629
PubChem Substance ID: 24873981
Properties
| Related Categories | A, A-B, AM to AQ, Alpha Sort, Alphabetic, |
| grade | analytical standard |
| vapor density | 3.22 (185 °C, vs air) |
| vapor pressure | 0.7 mmHg ( 25 °C) |
| assay | ≥99.5% (GC) |
| autoignition temp. | 1139 °F |
| shelf life | (limited shelf life, expiry date on the label) |
| expl. lim. | 11 % |
| total impurities | ≤0.1% water |
| <0.03% nitrobenzene (C6H5NO2) | |
| refractive index | n |
| n | |
| bp | 184 °C(lit.) |
| mp | −6 °C(lit.) |
| density | 1.022 g/mL at 25 °C(lit.) |
Description
Biochem/physiol Actions
The acute toxicity of aniline involves its activation in vivo to 4-hydroxyaniline and the formation of adducts with hemoglobin. In erythrocytes, this is associated with the release of iron and the accumulation of methemoglobin and the development of hemolytic anemia and inflammation of the spleen. Tumor formation is often observed in the spleen on prolonged administration.
Price and Availability
Documents
Certificate of Analysis
| FT-IR Condensed Phase |  |
| FT-IR Raman | |
| FT-NMR |  |
| Structure Search |  |
| Pressure-Temperature Nomograph |  |
| Similar Products |
Safety Information
| Symbol |     GHS05, GHS06, GHS08, GHS09 |
| Signal word | Danger |
| Hazard statements | H301-H311-H317-H318-H331-H341-H351-H372-H400 |
| Precautionary statements | P261-P273-P280-P301 + P310-P305 + P351 + P338-P311 |
| Personal Protective Equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
| Hazard Codes | T,N |
| Risk Statements | 23/24/25-40-41-43-48/23/24/25-50-68 |
| Safety Statements | 26-27-36/37/39-45-46-61-63 |
| RIDADR | UN 1547 6.1/PG 2 |
| WGK Germany | 2 |
| RTECS | BW6650000 |
| Flash Point(F) | 158 °F |
| Flash Point(C) | 70 °C |
Technical information & documentation associated with this product is available in the Safety & Documentation tab.
References
Zwirner-Baier, I., et al. , Biomonitoring of aromatic amines VI: determination of hemoglobin adducts after feeding aniline hydrochloride in the diet of rats for 4 weeks. Arch. Toxicol. 77, 672-67, (2003)
Ciccoli, L., et al., Hemolytic drugs aniline and dapsone induce iron release in erythrocytes and increase the free iron pool in spleen and liver. Toxicol. Lett. 110, 57-66, (1999)
Merck 14,659
Beil. 12,IV,223
Fieser 6,21
Aldrich MSDS 1, 125:D / Corp MSDS 1 (1), 270:A / FT-IR 1 (1), 1189:A / FT-IR 2 (2), 2024:A / FT-NMR 1 (2), 451:A / IR-Spectra (2), 630:A / IR-Spectra (3), 714:A / NMR-Reference 2 (1), 987:A / RegBook 1 (1), 1383:A / Sax 6, 280 / Sigma FT-IR 1 (2), 284:A / Structure Index 1, 214:A:1 / Vapor Phase 3, 1109:A
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